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Year : 2016  |  Volume : 3  |  Issue : 1  |  Page : 25-27

Asymptomatic HIV positive patient presenting with myelopathy


Department of Medicine, PBM Hospital and Associated Group of S. P. Medical College, Bikaner, Rajasthan, India

Correspondence Address:
Dr. Jatin Agrawal
Department of Medicine, PBM Hospital and Associated Group of S. P. Medical College, Bikaner - 334 001, Rajasthan
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2350-0298.184682

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A wide variety of disorders of diverse pathogenic mechanisms can trigger spinal cord dysfunction in HIV-1-infected patients. The most common such condition is HIV-1-associated myelopathy (HAM) which characteristically seen during advanced HIV infection in patients with low CD4 cell counts and previous AIDS-defining diagnoses. Histologically seen in approximately 30% of AIDS patients, but only 10% have clinical symptoms related to the disease. We describe an unusual case of HAM in previously asymptomatic patient with relatively low CD4 cell count (78 cells/mm3). The patient unaware of her seropositive status presented with a clinically slowly progressive myelopathy with difficulty in walking without assistance. We discharged a patient on antiretroviral therapy. We also review the disorders reported to derange spinal cord function in previously asymptomatic HIV-1 infected patients with preserved counts.


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