|Year : 2018 | Volume
| Issue : 2 | Page : 43-51
Suicide prevention strategies: An overview of current evidence and best practice elements
Vikas Menon1, Karthick Subramanian2, Nivedhitha Selvakumar1, Shivanand Kattimani1
1 Department of Psychiatry, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India
2 Department of Psychiatry, Mahatma Gandhi Medical College and Research Institute, Puducherry, India
|Date of Submission||14-Oct-2018|
|Date of Acceptance||03-Dec-2018|
|Date of Web Publication||31-Dec-2018|
Department of Psychiatry, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry - 605 006
Source of Support: None, Conflict of Interest: None
Suicide is a complex human behavior with multiple interacting determinants. Clinicians and practitioners often face difficulties in assimilating the evidence base for suicide prevention interventions, evaluating their effectiveness and decoding the best practice elements of each approach. In this article, we do not aim to provide an exhaustive coverage of every approach. Instead, we provide an overview of the following eight major suicide prevention interventions: awareness programs, screening, gatekeeper training, access to means restriction, follow-up care, hotlines, media strategies, pharmacotherapeutic and psychotherapeutic approaches. The evidence base and components of each approach are described to facilitate replication. The best practice elements are synthesized from each approach and presented to aid program development and practice. Although a number of approaches hold promise, there are difficulties in ascertaining the effective elements under each of them. Innovative research designs are needed to address this knowledge gap as it will facilitate optimal allocation of resources for suicide prevention.
Keywords: Attempted suicide, deliberate self-harm, India, prevention, suicide
|How to cite this article:|
Menon V, Subramanian K, Selvakumar N, Kattimani S. Suicide prevention strategies: An overview of current evidence and best practice elements. Int J Adv Med Health Res 2018;5:43-51
|How to cite this URL:|
Menon V, Subramanian K, Selvakumar N, Kattimani S. Suicide prevention strategies: An overview of current evidence and best practice elements. Int J Adv Med Health Res [serial online] 2018 [cited 2019 Sep 19];5:43-51. Available from: http://www.ijamhrjournal.org/text.asp?2018/5/2/43/249071
| Introduction|| |
Suicide is a major public health problem worldwide with complex multifactorial origins. More than 800,000 lives worldwide are lost to suicide every year, and Asia accounts for more than 60% of such deaths. India has seen a steady increase in the incidence of suicidal deaths in the last five decades. The estimated suicide-related death rate in India is 21/100,000, which is nearly twice the global average (11.4/100,000) and translates into more than 230,000 lives lost annually. Although these are worrying figures themselves, another equally concerning global phenomenon is the changing demographics associated with the malady. There is a clear shift in the predominance of suicides from the elderly to the younger people all over the word and particularly in India., Suicide is now the leading cause of mortality in India for those in the age group of 15–39 years. This not only fritters away the advantage of the demographic dividend, provided by the brimming younger population in our country, but also has massive socioeconomic costs and implications.
To tackle such a rapidly growing and multifaceted problem, no single strategy is likely to work best. Instead, a systematic, multipronged, collaborative prevention strategy that addresses population level as well as individual level factors is needed. In the past decade, much new literature had been added in this area. Robust research designs that evaluate these strategies and best practice elements from each strategy need to be synthesized in order to inform policymaking, deliverables, and action plans. The focus of this review is not to exhaustively cover the evidence base for each suicide prevention approach but to provide an overview of representative studies or, more importantly, systematic reviews that have explored each approach and describe the levels of intervention involved. In this review, wherever possible, we also outline the global best practice elements derived from an understanding of what works and what does not in each approach. This, in turn, will inform the development of local and national suicide prevention programs and spur further research to address critical knowledge gaps in this regard.
| Methods|| |
For this review, we conducted an electronic literature search of MEDLINE and the Cochrane Library for potentially relevant English language peer-reviewed articles published between January 1968 and September 2018 to identify relevant articles evaluating suicide prevention. The initial search was carried out using the Medical Subject Heading and free text term for “suicid*,” “prevent*,” and “review.” Subsequently, random combinations of “suicide” with the following keyword identifiers were used: Depression, gatekeeper, mass media, crisis hotline, pharmacotherapy, psychotherapy, means, methods, poisoning, screening, health promotion, education, and training. In addition, we also scrutinized the reference lists of selected articles to identify potentially relevant studies. The search was done by three reviewers independently and these were qualified psychiatrists.
Study selection and data extraction
The initial search by three independent reviewers yielded 26,139 hits. We included only articles in English language peer-reviewed journals which reported any of the following outcomes: attempted suicide, completed suicide, and suicidal ideation. As this was intended to be a narrative analysis to guide clinicians and researchers, we also included systematic reviews where the outcome was any of the aforementioned suicidal behaviors and the original articles included in these reviews were not examined separately. Case studies and gray literature such as conference proceedings were excluded due to the potential risk of incomplete information to derive the best practice elements. Based on these criteria and after elimination of duplicates, 151 articles were shortlisted for potential inclusion. Their full texts were examined by three independent reviewers and 98 articles were finally chosen for inclusion in the present review.
The reviewers examined the included articles for their content and grouped them into different subcategories of suicide prevention strategies according to their focus. This process led to a list of the following eight suicide prevention approaches to be covered in the review: education and awareness programs, screening programs, gatekeeper training, restricting access to means, media strategies, telephonic hotlines, pharmacotherapeutic and psychotherapeutic approaches, and follow-up care. The studies selected, results, and conclusions reached were agreed upon by all the authors. The best practice elements in each intervention were synthesized after assessing commonalities between individual reports. We did not assess the risk of bias for the individual studies or derive summary estimates as it was not the focus of the present review and besides, many included studies were reviews themselves. Below, we discuss the narrative results of the search under individual suicide prevention approaches separately, while [Table 1] summarizes the key best practice elements for each preventive approach.
|Table 1: Best practice elements of various suicide prevention strategies|
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| Results|| |
Suicide awareness programs
The ideal conditions for an effective awareness program include delivery in a relevant setting, having a multifaceted and comprehensive nature inclusive of community-based strategies, and adopting a universal approach while simultaneously ensuring identification of at-risk groups.,
For the lay public
Focused suicide awareness programs such as short talks for a 90-min period have been shown to enhance the identification of warning signs of suicide. Concurrent dissemination of educational material coupled with reaching out through media and training of gatekeepers appear more effective than the distribution of educational material alone. Sharing of patient and suicide survivor experiences is useful in enhancing awareness. Awareness programs for gatekeepers should involve education about risk factors, information on suicide support initiatives as well as legislations and initiatives to reduce stigma.,
Programs which are multipronged in approach such as the SEYLE awareness (empower pupils by increasing the awareness on general mental health and healthy and unhealthy behaviors) and Question, Persuade, and Refer (QPR) appear promising for suicide prevention, especially in adolescents. An interactive approach using focus group discussions and role plays was adopted in the “Surviving the Teens” method to provide awareness on suicidal burden, risk factors, helplines, and warning signs to students. Positive effects were noted on self-efficacy and help-seeking behaviors at 3 months postintervention.
While the above evidence generally supports the use of awareness strategies for suicide prevention, evidence for a favorable impact on subsequent health-seeking behaviors, a crucial outcome in suicide awareness activities, is mixed.,,
For medical and nursing professionals
Educating the primary care physicians in recognizing and responding to psychological distress and suicidal thoughts improves detection and enhances the treatment of depression, though mixed evidence also exists., Nevertheless, this seems an important strategy for suicide prevention as most people who die by suicide have contacted the primary care provider in the preceding month.,
Similarly, programs targeting mental health professionals and nursing professionals that highlighted postsuicide attempt counseling and restriction of means increased their knowledge, comfort, and counseling skills on suicide.
Screening programs for suicide prevention
Modest evidence shows that the screening tools employed can pick up high-risk adults and older adults at risk of suicide among the community. Notably, the sensitivity and specificity of the instrument play a key role in risk assessment., Contemporary suicide screening programs utilize specialized measures to identify at-risk youth for early referral and intervention. One of the most commonly used instruments is the Columbia-Suicide Severity Rating Scale - Screening version with a high degree of sensitivity and specificity, followed by Suicide Risk Screen and Diagnostic Interview Schedule for Children-IV.
The primary care setting and the emergency department (ED) are key areas where suicide screening must be implemented. The ED assessment should cover a wide range of screening measures for common medical conditions and should ideally incorporate suicide behavior assessment., The youth presenting to the ED and their parents/caregivers tend to support such comprehensive screening methods employed in the ED. Because depression is closely associated with suicidal risk, the same needs to be screened in any setting. Recent studies show positive effects due to screening measures, which are web-based and anonymous.,
Gatekeepers refer to individuals who regularly interact with potentially suicidal persons and are available to recognize the key behavioral clues indicating elevated suicide risk., Potential gatekeepers include teachers, peers, school support staff, and specifically appointed counselors. All of them have the common advantage of significant face-to-face contact time with large number of people in the community. Gatekeeper training for students includes elements of informing the suicidal burden, risk factors, warning signs, support system available, signs of depression, communication, and counseling skills to address at-risk population.
Group-based approaches to gatekeeper training with suicide awareness, referral sources, referral skills and QPR as components,,,, along with behavioral rehearsal have been described,,,, for diverse populations such as schoolchildren, college students, and veterans. The QPR model is widely used for gatekeeper training and shows consistent effects in improvement of suicide awareness and enhancing skills to deal with adolescents at-risk. Most studies reveal that training period of gatekeepers can be kept at 3 months,,,, with some studies following up the gatekeepers up to 6–9 months.,
Some of the challenges involved in assessing the effectiveness of gatekeeper training include determining the required levels of institutional support, paucity of randomized controlled trials in this area and measuring acquired learning. Moreover, questions remain on the durability of skills acquired from dedicated programs over the long term. For better results, gatekeeper programs must include a wide range of individuals such as the clergy, legal functionaries, and the police personnel.,
Restriction of access to means
Means restriction is an effective strategy to curb suicidal behaviors as it addresses the population at large including those in whom suicidal risk remains undetected. There can be various modes of restriction of means to suicide such as elimination of the potentially lethal agent, impediments or interferences to access, or sociocultural educational activities promoting suicide awareness.
Restriction of access to pesticides, substituting lethal pesticides with less lethal compounds, double-lock boxes, and nonpesticide agricultural movement preventing ready access to dangerous pesticides,, have been found to be effective. Community locker programs for pesticides where the pesticides are stored in lockers along with community involvement have led to reduced usage of pesticides and decreased suicidal deaths among rural farmers of India, though contrasting evidence is available from other countries.
With regard to firearms, evidence suggests that appealing to individuals against storing dangerous items such as firearms, avoiding giving them to at-risk individuals and enrolling the gun owner groups in programs to reduce the risk of suicide may be more effective than implementing punitive laws and stringent actions.,
Other methods tried include analgesic withdrawal from dispensaries, restricting sales of barbiturates and caffeine tablets to reduce overdose suicidal attempts, restricting measures on hanging, erection of barriers at jumping hotspots, and restricting access to charcoal., An unusual phenomenon arising out of means restriction is “means substitution” wherein the individual may simply substitute one suicide method with another. This could possibly be due to locoregional restrictions in the availability of specific means or overdiagnosis of suicidal risk in those who are in severe psychological distress and yet without contemplations on suicide.
It is also important to note that limitations exist for many of the above strategies to restrict means,,,, perhaps implying that no single strategy may work best.
The risk of suicide in the postdischarge period is quite high and has been observed in diverse populations (youth and adults) and periods. The suicide re-attempt rates are the highest in the 1st week, followed by the first 3 months postdischarge and may last up to 1–3 years from the present attempt., Evidence suggests that suicide patients who are discharged from the hospital can be provided various support and follow-up measures such as caring letters, postcards, frequent phone calls, text messaging, brief and regular sessions of supportive counseling, follow-up by mental health worker, and outreach programs., To target the survivors of suicide (peers/family), school administrators, teaching and nonteaching support staff, students, families, and the community need to participate in postvention or follow-up care services.,
Before embarking on a discussion about the state of evidence of suicide hotlines, it is necessary to understand what constitutes a hotline for suicide. A report by the California Department of Mental Health states that suicide prevention hotlines “provide phone-based services for individuals who are at risk of suicide or concerned about someone at risk of suicide.”
Overall, there is a dearth of evidence for the empirical effectiveness of telephonic and Internet-based suicide hotlines. Most available studies have either assessed hotlines among a group of other interventions for suicide prevention, which makes it difficult to isolate the effect of the hotline, or focused on diverse outcome measures such as acceptability, identification, and referral of people at risk as well as service barriers.
Studies comparing synchronous telephonic hotlines against asynchronous online support groups have found that suicide threats were significantly lesser in the hotline group. A randomized controlled trial conducted among callers, both young and elderly, to a suicide hotline that evaluated the efficacy of two types of brief telephonic psychotherapy concluded that telephonic psychotherapy was superior to waitlisted controls and that hotlines, when they employ professionals with focused training, are a viable option to deliver effective brief psychotherapy for distressed and suicidal callers.
Gould et al. carried out a research aimed at delineating the suicidal severity of adult suicide hotline users, end point severity following the call, as well as the nature and predictors of suicidality on follow-up. Contrary to popular perception, the service attracted seriously suicidal clients and mitigation of the suicidal desire as well as reduction in hopelessness was observed on follow-up.
A few studies have examined the prospective impact of suicide hotlines on suicide rates in the community. In one such study, the impact of a 24 × 7 suicide telephone hotline on suicide rates in the community of select towns where the program was started was examined. Each town was compared against a control town that was matched for socioeconomic parameters. The authors found a statistically significant decline in suicide rates in the towns where the intervention was carried out but not in the control towns, thus pointing to a positive impact of the program. Of note, the hotline was manned by lay workers who underwent specific training mainly aimed at determining if the service user required specialist referral.
In a study on the effectiveness of hotline services on linking callers to specialist mental health care units among adolescents and the elderly, it was found that the post call service utilization rate was nearly 50%. Additionally, the authors also concluded that hotline services may facilitate surmounting attitudinal and structural barriers to utilizing mental health-care services.
The helper behaviors and intervention styles that were found to be associated with better short-term outcomes among young and elderly users of crisis hotlines include an attitude of empathy, support, respect, and collaborative problem-solving rather than active listening. These findings have important implications for recruitment and training of helpline volunteers.
Media strategies for suicide prevention
Given the influence of media reporting on public perceptions and attitudes toward suicide, media-based approaches such as responsible reporting represent a population-level strategy for suicide prevention.
Evidence suggests that glorifying and graphic reporting of suicide, especially related to the suicide method used, can trigger imitative attempts by vulnerable people., Studies on depressed adults have also pointed to the characteristics of people who may be most vulnerable and impressionable in this regard; the young, currently depressed; and those who have attempted recently. Interestingly, studies, while showing a positive association between media reporting and emergent suicidal behavior, also showed a bidirectional relationship with protective effects in the general population (possibly related to an emphasis on healthy coping) and negative effects in vulnerable people.
Two systematic reviews, confirmed an association between media reporting and ensuing suicide. Further, one of the reviews found that adherence to guidelines reduces the phenomenon of imitative or “copycat” suicides. Wide variability in the impact of guidelines on suicide reporting quality has been observed. The authors concluded that collaborative, media-driven training approaches may have the best chances of success in reducing suicide. Collaboration with both national and regional media may be required for optimal results.
Based on the above evidence, the World Health Organization (WHO) and International Association of Suicide Prevention have framed guidelines for media reporting of suicide, mainly for use in countries that do not have national guidelines themselves. The Indian Psychiatric Society (IPS) has brought out a position statement on media coverage of suicides, which emphasizes collaboration between media professionals and medical professionals for better dissemination and impact. The major recommendations of the IPS position statement are as follows:
- Matter of fact, neutral reporting rather than sensationalism
- Discreet reporting (avoiding front page, small headline and without photographs) devoid of detailed description of the method used
- Sensitive to possible psychological harm on survivors and respecting their privacy
- Exercising restraint when reporting celebrity suicides.
In a rather negative indictment of media reporting practices in India, Jain and Kumar concluded that suicide reporting in India is inadequately adherent to the WHO guidelines and tends to veer toward sensationalism. These findings were subsequently endorsed in a larger study which noted several harmful suicide-reporting practices, such as explicit descriptions of methods used.
Psychotropics play a major role in reducing suicidal risk among psychiatric patients. They may be working primarily by controlling the symptoms of the underlying psychiatric disorder.
Depressive disorder is currently the most common cause of suicidal attempt among those with an underlying psychiatric disorder. Antidepressants are proven to be effective in reducing the suicidal risk among depressed patients.
Lithium, a mood stabilizer, has shown efficacy in reducing suicidal risk in both bipolar and depressive disorders. Though the exact mechanism of action is unknown, possible explanations include a secondary effect of relapse-rate reductions. The other possible mechanism is that it could increase serotonin levels in brain and confer ongoing protection.
The atypical antipsychotic clozapine is used primarily in the management of treatment-resistant schizophrenia. Its antisuicidal effects have been shown in adults with chronic schizophrenia and schizoaffective disorders. Here too, as for lithium, the putative mechanisms of action involve modulation of central serotonin levels, thereby favorably impacting suicidal risk. Preliminary evidence from adult studies exists for the antisuicidal properties of other antipsychotics such as olanzapine, quetiapine, ziprasidone, aripiprazole, and asenapine; nutraceutical agents such as omega 3 fatty acids; and anesthetic agents such as ketamine.,
Electroconvulsive therapy has proven rapid antisuicidal effects. Finally, positive evidence for combination strategies such as medications and psychotherapy for reducing depressive symptoms and suicide risk among adolescents is available from prospective trials such as the Treatment of Adolescent Suicide Attempters study. Ketamine, a noncompetitive N-methyl D-Aspartate antagonist, has been shown to have antisuicidal properties with a rapid onset of action. Based on this, a possible role for ketamine in suicide prevention, particularly in emergency settings, has been postulated. Key caveats here include short duration of the benefits observed with ketamine and the finding that its antisuicidal properties are linked to its antidepressant effects.
Psychotherapy is an important and evidence-based treatment modality in the management of suicidality. It has been particularly effective in the adult age group, those with borderline personality disorder (BPD), and those receiving outpatient treatment. The absolute risk reduction for suicidal events at follow-up with psychotherapeutic strategies was 6.59% when compared to treatment as usual.
Among the different types of psychotherapy, cognitive behavior therapy (CBT) has robust evidence in reducing the suicidal risk. In this technique, one aims at collaboratively exploring the reasons for a suicide attempt, applying techniques such as cognitive restructuring to alter dysfunctional cognitions, and enabling healthy coping. Maladaptive coping has previously been shown to be increased among impulsive adult suicide attempters. Common cognitive themes targeted among youths and adults include ideas of hopelessness, considering suicide as a solution for problems, a need to escape, and feelings of loneliness. In the recent past, third-wave CBT techniques such as mindfulness-based CBT techniques have been shown to be effective in reducing suicidal behavior among army veterans.
In suicidality associated with BPD, dialectical behavioral therapy (DBT), a form of CBT based on the principles of emotional regulation and interpersonal effectiveness, has been shown to be effective. A modified version of DBT to suit adolescents was found to be effective in rapidly resolving suicidal ideations in BPD and also had a long-term effect on reducing self-harm attempts.
Encouraging evidence also exists for interpersonal therapy, predicated upon links between stressful life events and mood, in the elderly, as well as problem-solving therapy in reducing suicidal ideations in adolescent people at risk for suicide.
Other novel intervention models with promising evidence for impact on suicide attempts include the following:
- Safe Alternatives for Teen and Youth – This approach employs principles from both CBT and DBT to promote safety among those attempting suicide in the adolescent age groups
- Attempted Suicide Short Intervention Program – This incorporates elements of therapeutic alliance, narrative style of interviewing, education about mental illness, safety measures, and regular letters for 2 years
- Collaborative Assessment and Management of Suicidality – This is an intervention to address suicidal ideations, for the older adolescents, adults, and elderly, in the inpatient setting, and has short-term effects in reducing further attempts
- Systems Training for Emotional Predictability and Problem Solving – This is a program which results in improvement in emotional regulation and thereby reduction of suicidal attempts in adults.
Combining the above strategies, we propose a multitier approach to suicide prevention [Figure 1]. This framework combines population-level (Tier 1), subpopulation-level (Tier 2), and individual-level (Tier 3) strategies. As one progresses from left to right of the schema, the strategies become more proximal and individually focused. This framework may help in designing a comprehensive approach to suicide prevention with adequate focus at the population as well as individual levels.
The strengths and limitations of the various suicide prevention approaches discussed here merit attention. While population- and subpopulation-level strategies such as public awareness and information programs as well as gatekeeper training may have broader cascading effects on the knowledge of risk factors, stigma, and help-seeking behaviors, evidence has shown limited effects on major outcomes of suicidal behavior or on intermediate outcomes such as help-seeking behaviors. As these are highly resource intensive approaches, there is a need to evaluate their long-term cost-effectiveness in a systematic manner. For screening programs, the major limitation is the lack of universally accepted and valid screening tools to assess suicide risk. Due to their significant potential to shape public opinion, media strategies such as responsible media reporting appear promising. However, the obvious limitation is that merely reporting suicide as per media reporting guidelines, without an educational component and collaboration of journalists with training and support groups, may not have the desired effect.
Restriction of access to means is an attractive method that can be implemented with legislation and public policy initiatives, but is limited by its suitability to contexts where the method is lethal, popular, and easily accessible as well as by the possibility of substitution of means. Moreover, in all likelihood, this is only a time-buying strategy and is likely to have an impact only when combined with other interventions. Helplines or hotlines can be used for the general population or vulnerable subgroups but, perhaps, the biggest constraints, especially in low-resource settings, are the availability of trained volunteers and peer support groups to optimize benefits.
Individual strategies such as pharmacotherapy and psychotherapy may not have population-level effects, and one must also keep in mind the potential risks such as aggravation of suicidal behavior in select populations such as children and adolescents. Interventions focusing on enhancing follow-up care for suicide offer the advantage of reducing burden on the patients and their caregivers as well as the larger health-care system. However, these approaches are limited by their emphasis on the involvement of family in after care and need for social connectedness.
| Conclusion|| |
Although several approaches have shown evidence for suicide prevention, it is likely that a combination of strategies may work better than isolated approaches. Given the low base rate of suicide in the population, challenges exist in evaluating and defining effective outcomes for interventions in suicide prevention. Many of the interventions described are multifaceted, and isolating the effective components in order to delineate the best practice elements in each strategy remains an arduous task. Clearly, more well-designed randomized controlled trials involving at-risk individuals may answer some of these questions. Cross-cultural translation of findings remain sketchy and more local evidence is needed to inform policy planning as ground-level factors and resources may vary between countries and settings. Ecological interventions for suicide prevention using mobile technology, while being globally relevant, may be the next potential game changer for resource-strapped settings in developing countries.
Financial support and sponsorship
Conflicts of interest
There are no conflicts of interest.
| References|| |
World Health Organization. Preventing Suicide: A Global Imperative. Geneva: World Health Organization; 2014.
Global Burden of Disease Pediatrics Collaboration, Kyu HH, Pinho C, Wagner JA, Brown JC, Bertozzi-Villa A, et al.
Global and national burden of diseases and injuries among children and adolescents between 1990 and 2013: Findings from the Global Burden of Disease 2013 study. JAMA Pediatr 2016;170:267-87.
Patel V, Ramasundarahettige C, Vijayakumar L, Thakur JS, Gajalakshmi V, Gururaj G, et al.
Suicide mortality in India: A nationally representative survey. Lancet 2012;379:2343-51.
Milner A, Page K, Spencer-Thomas S, Lamotagne AD. Workplace suicide prevention: A systematic review of published and unpublished activities. Health Promot Int 2015;30:29-37.
Jones S, Walker C, Miles AC, De Silva E, Zimitat C. A rural, community-based suicide awareness and intervention program. Rural Remote Health 2015;15:2972.
Tsai WP, Lin LY, Chang WL, Chang HC, Chou MC. The effects of the suicide awareness program in enhancing community volunteers' awareness of suicide warning signs. Arch Psychiatr Nurs 2010;24:63-8.
Dumesnil H, Verger P. Public awareness campaigns about depression and suicide: A review. Psychiatr Serv 2009;60:1203-13.
Menon V. Suicide risk assessment and formulation: An update. Asian J Psychiatr 2013;6:430-5.
Mann JJ, Apter A, Bertolote J, Beautrais A, Currier D, Haas A, et al.
Suicide prevention strategies: A systematic review. JAMA 2005;294:2064-74.
Wasserman C, Hoven CW, Wasserman D, Carli V, Sarchiapone M, Al-Halabí S, et al.
Suicide prevention for youth – A mental health awareness program: Lessons learned from the saving and empowering young lives in Europe (SEYLE) intervention study. BMC Public Health 2012;12:776.
King KA, Strunk CM, Sorter MT. Preliminary effectiveness of surviving the teens(®) suicide prevention and depression awareness program on adolescents' suicidality and self-efficacy in performing help-seeking behaviors. J Sch Health 2011;81:581-90.
Fountoulakis KN, Gonda X, Rihmer Z. Suicide prevention programs through community intervention. J Affect Disord 2011;130:10-6.
Lin EH, Simon GE, Katzelnick DJ, Pearson SD. Does physician education on depression management improve treatment in primary care? J Gen Intern Med 2001;16:614-9.
Thompson C, Kinmonth AL, Stevens L, Peveler RC, Stevens A, Ostler KJ, et al.
Effects of a clinical-practice guideline and practice-based education on detection and outcome of depression in primary care: Hampshire depression project randomised controlled trial. Lancet 2000;355:185-91.
Luoma JB, Martin CE, Pearson JL. Contact with mental health and primary care providers before suicide: A review of the evidence. Am J Psychiatry 2002;159:909-16.
Andersen UA, Andersen M, Rosholm JU, Gram LF. Contacts to the health care system prior to suicide: A comprehensive analysis using registers for general and psychiatric hospital admissions, contacts to general practitioners and practising specialists and drug prescriptions. Acta Psychiatr Scand 2000;102:126-34.
Sale E, Hendricks M, Weil V, Miller C, Perkins S, McCudden S, et al.
Counseling on access to lethal means (CALM): An evaluation of a suicide prevention means restriction training program for mental health providers. Community Ment Health J 2018;54:293-301.
O'Connor E, Gaynes BN, Burda BU, Soh C, Whitlock EP. Screening for and treatment of suicide risk relevant to primary care: A systematic review for the U.S. Preventive services task force. Ann Intern Med 2013;158:741-54.
Robinson J, Cox G, Malone A, Williamson M, Baldwin G, Fletcher K, et al.
Asystematic review of school-based interventions aimed at preventing, treating, and responding to suicide-related behavior in young people. Crisis 2013;34:164-82.
Cooper GD, Clements PT, Holt K. A review and application of suicide prevention programs in high school settings. Issues Ment Health Nurs 2011;32:696-702.
Horowitz LM, Ballard ED, Pao M. Suicide screening in schools, primary care and emergency departments. Curr Opin Pediatr 2009;21:620-7.
Babeva K, Hughes JL, Asarnow J. Emergency department screening for suicide and mental health risk. Curr Psychiatry Rep 2016;18:100.
Hawley LD, MacDonald MG, Wallace EH, Smith J, Wummel B, Wren PA. Baseline assessment of campus-wide general health status and mental health: Opportunity for tailored suicide prevention and mental health awareness programming. J Am Coll Health 2016;64:174-83.
Moutier C, Norcross W, Jong P, Norman M, Kirby B, McGuire T, et al.
The suicide prevention and depression awareness program at the University of California, San Diego school of medicine. Acad Med 2012;87:320-6.
Burnette C, Ramchand R, Ayer L. Gatekeeper training for suicide prevention: A Theoretical model and review of the empirical literature. Rand Health Q 2015;5:16.
Shanta Bridges L, Sharma M, Lee JH, Bennett R, Buxbaum SG, Reese-Smith J, et al.
Using the PRECEDE-PROCEED model for an online peer-to-peer suicide prevention and awareness for depression (SPAD) intervention among African American college students: Experimental study. Health Promot Perspect 2018;8:15-24.
Matthieu MM, Cross W, Batres AR, Flora CM, Knox KL. Evaluation of gatekeeper training for suicide prevention in veterans. Arch Suicide Res 2008;12:148-54.
Wyman PA, Brown CH, Inman J, Cross W, Schmeelk-Cone K, Guo J, et al.
Randomized trial of a gatekeeper program for suicide prevention: 1-year impact on secondary school staff. J Consult Clin Psychol 2008;76:104-15.
Tompkins TL, Witt J, Abraibesh N. Does a gatekeeper suicide prevention program work in a school setting? Evaluating training outcome and moderators of effectiveness. Suicide Life Threat Behav 2009;39:671-81.
Cerel J, Padgett JH, Robbins V, Kaminer B. A state's approach to suicide prevention awareness: Gatekeeper training in Kentucky. J Evid Based Soc Work 2012;9:283-92.
Siau CS, Wee LH, Ibrahim N, Visvalingam U, Yeap LL, Wahab S. Gatekeeper suicide training's effectiveness among Malaysian hospital health professionals: A control group study with a three-month follow-up. J Contin Educ Health Prof 2018;38:227-34.
Cross W, Matthieu MM, Lezine D, Knox KL. Does a brief suicide prevention gatekeeper training program enhance observed skills? Crisis 2010;31:149-59.
Cross WF, Seaburn D, Gibbs D, Schmeelk-Cone K, White AM, Caine ED, et al.
Does practice make perfect? A randomized control trial of behavioral rehearsal on suicide prevention gatekeeper skills. J Prim Prev 2011;32:195-211.
Pasco S, Wallack C, Sartin RM, Dayton R. The impact of experiential exercises on communication and relational skills in a suicide prevention gatekeeper-training program for college resident advisors. J Am Coll Health 2012;60:134-40.
Cimini MD, Rivero EM, Bernier JE, Stanley JA, Murray AD, Anderson DA, et al.
Implementing an audience-specific small-group gatekeeper training program to respond to suicide risk among college students: A case study. J Am Coll Health 2014;62:92-100.
Litteken C, Sale E. Long-term effectiveness of the question, persuade, refer (QPR) suicide prevention gatekeeper training program: Lessons from Missouri. Community Ment Health J 2018;54:282-92.
Stuart C, Waalen JK, Haelstromm E. Many helping hearts: An evaluation of peer gatekeeper training in suicide risk assessment. Death Stud 2003;27:321-33.
Condron S, Godoy Garraza L, Kuiper N, Sukumar B, Walrath C, McKeon R. Comparing the effectiveness of brief versus in-depth gatekeeper training on behavioral outcomes for trainees. Crisis 2018. doi: 10.1027/0227-5910/a000539. [Epub ahead of print].
Rallis BA, Esposito-Smythers C, Disabato DJ, Mehlenbeck RS, Kaplan S, Geer L, et al.
Abrief peer gatekeeper suicide prevention training: Results of an open pilot trial. J Clin Psychol 2018;74:1106-16.
Ewell Foster CJ, Burnside AN, Smith PK, Kramer AC, Wills A, A King C. Identification, response, and referral of suicidal youth following applied suicide intervention skills training. Suicide Life Threat Behav 2017;47:297-308.
Brown RC, Straub J, Bohnacker I, Plener PL. Increasing knowledge, skills, and confidence concerning students' suicidality through a gatekeeper workshop for school staff. Front Psychol 2018;9:1233.
Arensman E, Coffey C, Griffin E, Van Audenhove C, Scheerder G, Gusmao R, et al.
Effectiveness of depression-suicidal behaviour gatekeeper training among police officers in three European regions: Outcomes of the optimising suicide prevention programmes and their implementation in Europe (OSPI-Europe) study. Int J Soc Psychiatry 2016;62:651-60.
Mason K, Geist M, Kuo R, Marshall D, Wines JD Jr. Predictors of clergy's ability to fulfill a suicide prevention gatekeeper role. J Pastoral Care Counsel 2016;70:34-9.
Yip PS, Caine E, Yousuf S, Chang SS, Wu KC, Chen YY. Means restriction for suicide prevention. Lancet 2012;379:2393-9.
Zalsman G, Hawton K, Wasserman D, van Heeringen K, Arensman E, Sarchiapone M, et al.
Suicide prevention strategies revisited: 10-year systematic review. Lancet Psychiatry 2016;3:646-59.
Reifels L, Mishara BL, Dargis L, Vijayakumar L, Phillips MR, Pirkis J. Outcomes of community-based suicide prevention approaches that involve reducing access to pesticides: A systematic literature review. Suicide Life Threat Behav 2018. doi: 10.1111/sltb.12503. [Epub ahead of print].
Vijayakumar L, Jeyaseelan L, Kumar S, Mohanraj R, Devika S, Manikandan S. Acentral storage facility to reduce pesticide suicides – A feasibility study from India. BMC Public Health 2013;13:850.
Pearson M, Metcalfe C, Jayamanne S, Gunnell D, Weerasinghe M, Pieris R, et al.
Effectiveness of household lockable pesticide storage to reduce pesticide self-poisoning in rural Asia: A community-based, cluster-randomised controlled trial. Lancet 2017;390:1863-72.
Barber CW, Miller MJ. Reducing a suicidal person's access to lethal means of suicide: A research agenda. Am J Prev Med 2014;47:S264-72.
Jin HM, Khazem LR, Anestis MD. Recent advances in means safety as a suicide prevention strategy. Curr Psychiatry Rep 2016;18:96.
McPhedran S, Baker J. Suicide prevention and method restriction: Evaluating the impact of limiting access to lethal means among young Australians. Arch Suicide Res 2012;16:135-46.
Daigle MS. Suicide prevention through means restriction: Assessing the risk of substitution. A critical review and synthesis. Accid Anal Prev 2005;37:625-32.
Ho TP. The suicide risk of discharged psychiatric patients. J Clin Psychiatry 2003;64:702-7.
Ghanbari B, Malakouti SK, Nojomi M, Alavi K, Khaleghparast S. Suicide prevention and follow-up services: A narrative review. Glob J Health Sci 2015;8:145-53.
Chung DT, Ryan CJ, Hadzi-Pavlovic D, Singh SP, Stanton C, Large MM. Suicide rates after discharge from psychiatric facilities: A systematic review and meta-analysis. JAMA Psychiatry 2017;74:694-702.
Brown GK, Green KL. A review of evidence-based follow-up care for suicide prevention: Where do we go from here? Am J Prev Med 2014;47:S209-15.
Dunne-Maxim K, Godin S, Lamb F, Sutton C, Underwood M. The aftermath of youth suicide – Providing postvention services for the school and community. Crisis 1992;13:16-22.
Andriessen K, Krysinska K. Essential questions on suicide bereavement and postvention. Int J Environ Res Public Health 2012;9:24-32.
Gilat I, Shahar G. Emotional first aid for a suicide crisis: Comparison between telephonic hotline and internet. Psychiatry 2007;70:12-8.
Rhee WK, Merbaum M, Strube MJ, Self SM. Efficacy of brief telephone psychotherapy with callers to a suicide hotline. Suicide Life Threat Behav 2005;35:317-28.
Gould MS, Kalafat J, Harrismunfakh JL, Kleinman M. An evaluation of crisis hotline outcomes. Part 2: Suicidal callers. Suicide Life Threat Behav 2007;37:338-52.
Bagley C. The evaluation of a suicide prevention scheme by an ecological method. Soc Sci Med 1968;2:1-4.
Gould MS, Munfakh JL, Kleinman M, Lake AM. National suicide prevention lifeline: Enhancing mental health care for suicidal individuals and other people in crisis. Suicide Life Threat Behav 2012;42:22-35.
Mishara BL, Chagnon F, Daigle M, Balan B, Raymond S, Marcoux I, et al.
Which helper behaviors and intervention styles are related to better short-term outcomes in telephone crisis intervention? Results from a silent monitoring study of calls to the U.S 1-800-SUICIDE network. Suicide Life Threat Behav 2007;37:308-21.
Pirkis J, Blood RW, Beautrais A, Burgess P, Skehans J. Media guidelines on the reporting of suicide. Crisis 2006;27:82-7.
Niederkrotenthaler T, Voracek M, Herberth A, Till B, Strauss M, Etzersdorfer E, et al.
Role of media reports in completed and prevented suicide: Werther v. Papageno effects. Br J Psychiatry 2010;197:234-43.
Cheng AT, Hawton K, Chen TH, Yen AM, Chang JC, Chong MY, et al.
The influence of media reporting of a celebrity suicide on suicidal behavior in patients with a history of depressive disorder. J Affect Disord 2007;103:69-75.
Bohanna I, Wang X. Media guidelines for the responsible reporting of suicide: A review of effectiveness. Crisis 2012;33:190-8.
Sisask M, Värnik A. Media roles in suicide prevention: A systematic review. Int J Environ Res Public Health 2012;9:123-38.
Niederkrotenthaler T, Sonneck G. Assessing the impact of media guidelines for reporting on suicides in Austria: Interrupted time series analysis. Aust N Z J Psychiatry 2007;41:419-28.
World Health Organization. Preventing Suicide: A Resource for Media Professionals. Geneva, Switzerland: International Association for Suicide Prevention (IASP): World Health Organization. Department of Mental Health and Substance Abuse; 2008.
Ramadas S, Kuttichira P, John CJ, Isaac M, Kallivayalil RA, Sharma I, et al.
Position statement and guideline on media coverage of suicide. Indian J Psychiatry 2014;56:107-10.
] [Full text]
Jain N, Kumar S. Is suicide reporting in Indian newspapers responsible? A study from Rajasthan. Asian J Psychiatr 2016;24:135-8.
Armstrong G, Vijayakumar L, Niederkrotenthaler T, Jayaseelan M, Kannan R, Pirkis J, et al.
Assessing the quality of media reporting of suicide news in India against World Health Organization guidelines: A content analysis study of nine major newspapers in Tamil Nadu. Aust N Z J Psychiatry 2018;52:856-63.
Rihmer Z, Gonda X. Prevention of depression-related suicides in primary care. Psychiatr Hung 2012;27:72-81.
Riesselman A, Johnson E, Palmer E. Lithium and clozapine in suicidality: Shedding some light to get out of the dark. Ment Health Clin 2015;5:237-43.
Lauterbach E, Felber W, Müller-Oerlinghausen B, Ahrens B, Bronisch T, Meyer T, et al.
Adjunctive lithium treatment in the prevention of suicidal behaviour in depressive disorders: A randomised, placebo-controlled, 1-year trial. Acta Psychiatr Scand 2008;118:469-79.
Spivak B, Shabash E, Sheitman B, Weizman A, Mester R. The effects of clozapine versus haloperidol on measures of impulsive aggression and suicidality in chronic schizophrenia patients: An open, nonrandomized, 6-month study. J Clin Psychiatry 2003;64:755-60.
Pompili M, Baldessarini RJ, Forte A, Erbuto D, Serafini G, Fiorillo A, et al.
Do atypical antipsychotics have antisuicidal effects? A hypothesis-generating overview. Int J Mol Sci 2016;17. pii: E1700.
Lewis MD, Hibbeln JR, Johnson JE, Lin YH, Hyun DY, Loewke JD. Suicide deaths of active-duty US military and omega-3 fatty-acid status: A case-control comparison. J Clin Psychiatry 2011;72:1585-90.
Fink M, Kellner CH, McCall WV. The role of ECT in suicide prevention. J ECT 2014;30:5-9.
Vitiello B, Brent DA, Greenhill LL, Emslie G, Wells K, Walkup JT, et al.
Depressive symptoms and clinical status during the treatment of adolescent suicide attempters (TASA) study. J Am Acad Child Adolesc Psychiatry 2009;48:997-1004.
Bartoli F, Riboldi I, Crocamo C, Di Brita C, Clerici M, Carrà G. Ketamine as a rapid-acting agent for suicidal ideation: A meta-analysis. Neurosci Biobehav Rev 2017;77:232-6.
Sathyanarayana Rao TS, Andrade C. A possible role for ketamine in suicide prevention in emergency and mainstream psychiatry. Indian J Psychiatry 2017;59:259-61.
Meerwijk EL, Parekh A, Oquendo MA, Allen IE, Franck LS, Lee KA, et al.
Direct versus indirect psychosocial and behavioural interventions to prevent suicide and suicide attempts: A systematic review and meta-analysis. Lancet Psychiatry 2016;3:544-54.
Wasserman D, Rihmer Z, Rujescu D, Sarchiapone M, Sokolowski M, Titelman D, et al.
The European psychiatric association (EPA) guidance on suicide treatment and prevention. Neuropsychopharmacol Hung 2012;14:113-36.
Lindner R, Schneider B. Psychotherapy of suicidality. Nervenarzt 2016;87:488-95.
Kattimani S, Sarkar S, Rajkumar RP, Menon V. Stressful life events, hopelessness, and coping strategies among impulsive suicide attempters. J Neurosci Rural Pract 2015;6:171-6.
] [Full text]
Adler A, Bush A, Barg FK, Weissinger G, Beck AT, Brown GK, et al.
Amixed methods approach to identify cognitive warning signs for suicide attempts. Arch Suicide Res 2016;20:528-38.
Kline A, Chesin M, Latorre M, Miller R, St Hill L, Shcherbakov A, et al.
Rationale and study design of a trial of mindfulness-based cognitive therapy for preventing suicidal behavior (MBCT-S) in military veterans. Contemp Clin Trials 2016;50:245-52.
Mehlum L, Ramberg M, Tørmoen AJ, Haga E, Diep LM, Stanley BH, et al.
Dialectical behavior therapy compared with enhanced usual care for adolescents with repeated suicidal and self-harming behavior: Outcomes over a one-year follow-up. J Am Acad Child Adolesc Psychiatry 2016;55:295-300.
Markowitz JC, Weissman MM. Interpersonal psychotherapy: Principles and applications. World Psychiatry 2004;3:136-9.
Heisel MJ, Talbot NL, King DA, Tu XM, Duberstein PR. Adapting interpersonal psychotherapy for older adults at risk for suicide. Am J Geriatr Psychiatry 2015;23:87-98.
Burns J, Dudley M, Hazell P, Patton G. Clinical management of deliberate self-harm in young people: The need for evidence-based approaches to reduce repetition. Aust N Z J Psychiatry 2005;39:121-8.
Asarnow JR, Hughes JL, Babeva KN, Sugar CA. Cognitive-behavioral family treatment for suicide attempt prevention: A randomized controlled trial. J Am Acad Child Adolesc Psychiatry 2017;56:506-14.
Michel K, Valach L, Gysin-Maillart A. A novel therapy for people who attempt suicide and why we need new models of suicide. Int J Environ Res Public Health 2017;14. pii: E243.
Ellis TE, Rufino KA, Allen JG. A controlled comparison trial of the collaborative assessment and management of suicidality (CAMS) in an inpatient setting: Outcomes at discharge and six-month follow-up. Psychiatry Res 2017;249:252-60.
Boccalon S, Alesiani R, Giarolli L, Fossati A. Systems training for emotional predictability and problem solving program and emotion dysregulation: A pilot study. J Nerv Ment Dis 2017;205:213-6.
Bertolote JM. Suicide prevention: At what level does it work? World Psychiatry 2004;3:147-51.
Jureidini JN, Doecke CJ, Mansfield PR, Haby MM, Menkes DB, Tonkin AL, et al.
Efficacy and safety of antidepressants for children and adolescents. BMJ 2004;328:879-83.
van der Feltz-Cornelis CM, Sarchiapone M, Postuvan V, Volker D, Roskar S, Grum AT, et al.
Best practice elements of multilevel suicide prevention strategies: A review of systematic reviews. Crisis 2011;32:319-33.