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 Table of Contents  
Year : 2015  |  Volume : 2  |  Issue : 1  |  Page : 59-60

Multiple splenic abscesses

1 Department of Medicine, Sarder Patel Medical College, Bikaner, Rajasthan, India
2 Department of Medicine, Dr. Sampurnanand Medical College, Jodhpur, Rajasthan, India

Date of Web Publication23-Jun-2015

Correspondence Address:
Dr. Harish Kumar
Department of Medicine, PBM Hospital, Bikaner, Rajasthan - 334 001
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2349-4220.159157

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Splenic abscess is a rare clinical entity with poor prognosis. But owing to imaging technique, diagnosis and prognosis have improved nowadays. Most patients who are presented with splenic abscess are immunocompromised due to predisposing risk factors like diabetes mellitus, intravenous drug abuse, trauma, bacterial endocarditis, human immunodeficiency virus (HIV), chemotherapy, or steroids. Here, we are presenting a rarer case of multiple splenic abscesses with its complication in an immunocompetent healthy adult male without any risk factor.

Keywords: Immunocompetent, multiple, splenectomy, splenic abscess

How to cite this article:
Kumar H, Singh VB, Meena BL, Pahadiya H, Singh K, Kumar R. Multiple splenic abscesses. Int J Adv Med Health Res 2015;2:59-60

How to cite this URL:
Kumar H, Singh VB, Meena BL, Pahadiya H, Singh K, Kumar R. Multiple splenic abscesses. Int J Adv Med Health Res [serial online] 2015 [cited 2018 Mar 23];2:59-60. Available from: http://www.ijamhrjournal.org/text.asp?2015/2/1/59/159157

  Introduction Top

Splenic abscess is a rare clinical problem with 800 reported cases in the international literature with high mortality if left untreated. [1],[2] In an autopsy series, its incidence was 0.14-0.7%. [3] The incidence of splenic abscess increased owing to the advanced imaging technique. [4] Most patients were presented with compromised immune system. The clinical manifestations of splenic abscess are left upper quadrant pain, fever, nausea, and vomiting. Fever is the most prominent symptom (present in up to 95% of cases) in splenic abscess. But in our case, the patient had only nonspecific complaints of abdominal pain with ascites, melena without fever, nausea, and vomiting for 7 days. Surgery is the gold standard treatment for multiple abscesses.

  Case Report Top

A 25-year-old male without any past medical history was admitted to the department of medicine with the chief complaint of left upper quadrant pain for 7days without any additional symptoms. His past medical history was free of any chronic illness and risk factor. Clinical examination revealed localized point tenderness and pain in the left hypochondria. His abdomen was soft and distended. His pulse rate was 90 beats per minute, respiration rate was 16 regular breaths per minute, and blood pressure was 110/80 mmHg. Chest and cardiac auscultations were normal. Laboratory study revealed polymorphous leukocytosis while the other tests were within normal limits. In erect posture, the chest and abdomen x-ray were normal. Echocardiography was normal. Abdominopelvic ultrasound sonography (USG) showed multiple hypoechoic heterogenous spaces occupying the cystic lesions, among which the largest was 3.5 cm × 3.0 cm with minimal intestinal free fluid. Contrast-enhanced computed tomography (CECT) of the abdomen showed a mildly enlarged spleen and a large peripherally enhancing cystic lesion of approximate size 107 mm × 71 mm × 91 mm in the mid and the lower pole of the spleen with internal air loculi communicating to the perisplenic collection [Figure 1]a and b. The liver, the pancreas, and the kidney were normal in both computed tomography (CT) and USG.
Figure 1: (a and b) CECT abdomen showing multiple splenic abscesses

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Broad spectrum antibiotics were started with aerobic and anaerobic coverages. Splenectomy was done after being vaccinated with pneumococcal vaccine; meanwhile, the antibiotics were continued. There were two large abscesses with multiple small abscesses pointing to the periphery. The fluid was taken for microscopy and culture; however, no organism was grown on culture. The histopathological study of the spleen revealed that the cause of these multiple splenic abscesses was nonspecific inflammatory process. The patient was discharged after 12 days of surgery.

  Discussion Top

Splenic abscess comprise a rare clinical entity with incidence of 0.14-0.7% in autopsy series. [3] The prognosis is poor in spite of early diagnosis by imaging and can reach 100% if untreated. Solitary splenic abscess is rare and multiple splenic abscesses are very rare in clinical practice. [2],[5],[6] Multiple splenic abscesses with unclear etiology are extremely rare in an immunocompetent host. [6],[7] Our patient was healthy without any risk factor diagnosed by USG and confirmed by CT abdomen. A recent study in 2008 put splenic abscess as a rare entity with only 600 cases described in the international literature. [2] Most of the studies that have been published earlier include the synchronous presence of conditions that compromise the immune system such as endocarditis, diabetes mellitus, congenital or acquired immunodeficiency, the administration of immunosuppressive medication as well as trauma. [1],[2],[8],[9],[10] Splenectomy is the gold standard treatment for multiple splenic abscesses. Although sonography-guided percutaneous drainage and drainage with antibiotics are options in selected patients, [9] the prognosis is better with splenectomy than with drainage in multiple splenic abscesses.

The Staphylococcus, Streptococcus, and gram-negative aerobic bacteria are the leading causes of splenic abscess.

We could not find out the etiology and pathophysiologic mechanism of splenic abscess in our patient. Our patient had multiple splenic abscesses and so hematogenous spread may have caused them, although both blood and abscess fluid cultures were negative. Most probably, it is the secondary complication with obscure primary etiology.

  Conclusion Top

Splenic abscess is an uncommon problem in clinical practice with high mortality in spite of early diagnosis. So, splenic abscess should be suspected in a patient with left upper quadrant pain and tenderness. Multiple splenic abscesses with high mortality rate are very rare in clinical practice. So, early suspicion and diagnosis and the prompt use of antibiotics improve the prognosis. Splenectomy is safe and the gold standard treatment for multiple splenic abscesses.

  Acknowledgment Top

We owe special thanks to Dr. Kulvindra Singh.

  References Top

Ng CY, Leong EC, Chng HC. Ten-year series of splenic abscesses in a general hospital in Singapore. Ann Acad Med Singapore 2008;37:749-52.  Back to cited text no. 1
Fotiadis C, Lavranos G, Patapis P, Karatzas G. Abscesses of the spleen: Report of three cases. World J Gastroenterol 2008;14: 3088-91.   Back to cited text no. 2
Chun CH, Raff MJ, Contreras L, Varghese R, Waterman N, Daffner R, et al. Splenic abscess. Medicine (Baltimore) 1980; 59:50-65.  Back to cited text no. 3
Teich S, Oliver GC, Canter JW. The early diagnosis of splenic abscess. Am Surg 1986;52:303-7.  Back to cited text no. 4
Warshauer DM, Hall HL. Solitary splenic lesions. Semin Ultrasound CT MR 2006;27:370-88.  Back to cited text no. 5
Kamaya A, Weinstein S, Desser TS. Multiple lesions of the spleen: Differential diagnosis of cystic and solid lesions. Semin Ultrasound CT MR 2006;27:389-403.  Back to cited text no. 6
Baños Madrid R, Gallardo Sánchez F, Albaladejo Meroño A, Vargas Acosta A, Carballo Alvárez F. Multiple splenic abscesses. Acta Gastroenterol Latinoam 2006;36:202-4.  Back to cited text no. 7
Green BT. Splenic abscess: Report of six cases and review of the literature. Am Surg 2001;67:80-5.  Back to cited text no. 8
Iñiguez A, Butte JM, Zuñiga JM, Torres J, Llanos O. Splenic abscesses. Report of seven cases. Rev Med Chil 2008;136:38-43.   Back to cited text no. 9
Chang KC, Chuah SK, Changchien CS, Tsai TL, Lu SN, Chiu YC, et al. Clinical characteristics and prognostic factors of splenic abscess: A review of 67 cases in a single medical center of Taiwan. World J Gastroenterol 2006;12:460-4.  Back to cited text no. 10


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